Blar i forfatter "Dale, Anders M"

Viser treff 1-2 av 2

    • Meta-analysis of Alzheimer’s disease on 9,751 samples from Norway and IGAP study identifies four risk loci 

      Witoelar, Aree; Rongve, Arvid; Almdahl, Ina Selseth; Ulstein, Ingun; Engvig, Andreas; White, Linda Rosemary; Selbæk, Geir; Stordal, Eystein; Andersen, Fredrik; Brækhus, Anne; Saltvedt, Ingvild; Engedal, Knut; Hughes, Timothy; Bergh, Sverre; Bråthen, Geir; Bogdanovic, Nenad; Bettella, Francesco; Wang, Yunpeng; Athanasiu, Lavinia; Bahrami, Shahram; Le Hellard, Stephanie; Giddaluru, Sudheer; Dale, Anders M; Sando, Sigrid Botne; Steinberg, Stacy; Stefansson, Hreinn; Snaedal, Jon; Desikan, Rahul S; Stefansson, Kari; Aarsland, Dag; Djurovic, Srdjan; Fladby, Tormod; Andreassen, Ole Andreas (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-27)
      A large fraction of genetic risk factors for Alzheimer’s Disease (AD) is still not identified, limiting the understanding of AD pathology and study of therapeutic targets. We conducted a genome-wide association study (GWAS) of AD cases and controls of European descent from the multi-center DemGene network across Norway and two independent European cohorts. In a two-stage process, we first performed ...

    • Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities 

      Steen, Nils Eiel; Rahman, Zillur; Szabo, Attila; Hindley, Guy; Parker, Nadine; Cheng, Weiqiu; Lin, Aihua; O'Connell, Kevin S; Sheikh, Mashhood Ahmed; Shadrin, Alexey; Bahrami, Shahram; Karthikeyan, Sandeep; Hoseth, Eva Zsuzsanna; Dale, Anders M; Aukrust, Pål; Smeland, Olav Bjerkehagen; Ueland, Thor; Frei, Oleksandr; Djurovic, Srdjan; Andreassen, Ole (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-06-15)
      Background - Immune mechanisms are indicated in schizophrenia (SCZ). Recent genome-wide association studies (GWAS) have identified genetic variants associated with SCZ and immune-related phenotypes. Here, we use cutting edge statistical tools to identify shared genetic variants between SCZ and white blood cell (WBC) counts and further understand the role of the immune system in SCZ.<p> <p>Study ...